Blood Test for Hypothyroidism Symptoms
Hypothyroidism is the condition related to the insufficient production of thyroid hormones by thyroid gland. Literally hypo means less or under and thyroidism is the condition related to thyroid gland. Making it together, hypothyroidism is condition where thyroid gland works less or it produces the thyroid hormones in an inadequate amount.
There are many causes involved in the hypothyroidism. Primary hypothyroidism is due to inflammation of the thyroid gland and insufficient production of the thyroid hormones where as, the secondary hypothyroidism could be due to any surgical removal of the gland or any other underlying disease. In some advanced stage, you may get the swelling over the neck and more severe, a person who is suffering from hypothyroidism may go under coma which needs immediate diagnosing and treatment. The hormonal levels in this patient are highly disturbed and are to be corrected as early as possible.
The symptoms of hypothyroidism get developed slowly. However, all the symptoms are difficult to notice at a time and hence it is always advisable to depend on the blood test. There are certain blood test, through which diagnose is carried out for hypothyroidism. These blood tests are performed in laboratories.
The thyroid gland uses iodine which is mostly available from the diet in foods like bread, salt and seafood to produce thyroid hormones. There are two most important thyroid hormones; triiodothyronine called as T3 and thyroxine called as T4 which estimates 0.1% and 99.9% present in our body respectively. However, the most biological activity is with T3 hormone. After getting released, large amount of T4 is converted into T3 which is an active hormone affecting the metabolism of cells.
In the case of hypothyroidism, the thyroid hormones are significantly found low in the blood. The TSH (Thyroid Stimulating Hormone) is to be tested. This TSH is made up by specialized cells in the pituitary called thyrotrophs. Thyrotrophs are highly sensitive to the amount of the thyroid hormones that is circulating in the blood. If the thyroid hormones drop, the pituitary gland makes more TSH to stimulate the thyroid gland to work more hard and to make thyroid hormone more. So, an increased level of TSH strongly suggests evidence of hypothyroidism. If the level of TSH is 6 or more, it is generally labeled as hypothyroidism as compare to 0.5-2.5 which is normal level for an individual. T3 and T4 levels are also altered from its normal value which is normal adult range 4-12 ug/dl for T4 and T3 uptake is 27-47%. Sometimes Free T4 index (T7) is also noted which comes 4-12 as normal adult range.
It is believed that these hormonal values help to diagnose the hypothyroidism. But there is one more sophisticated test that can reveal even mild low thyroid. This is called as TRH – Thyrotropin Releasing Hormone test. The entire procedure for this test requires an injection, which is followed by one or more blood drawing at 15, 30 and 45 minutes intervals. The test is very accurate but is comparatively costly and inconvenient for both the lab and patient.
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